The effect of cyclosporine on asymmetric antibodies and serum transforming growth factor beta1 in abortion-prone model of mice CBA/J x DBA/2

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چکیده

كچ ي هد فده و هقباس : ي ک ي طقس زورب للع زا اه ي ،ررکم ا لماوع تلاخد ي ژولونوم ي ک ا رد ي ن قم طققس عون ي وراد دقشاب ي س ي روپسولک ي ،ن ح لدم رد طقس شهاک بجوم ي ناو ي CBA/j×DBA/2 م ي تنآ ددرگ ي داب ي اه ي ان و راققتم TGF-β لماوع زا عت مهم يي ن گلماح تشونرس هدننک ي سررب روظنم هب رضاح هعلاطم تسا ي ات ث ي ر اس ي روپسولک ي ن م رب ي از ا ي ن تنآ عون ي داب ي س و اه ي اکوت ي ن TGF-β1 مرس ي ، ح لدم رد ي ناو ي تفرگ ماجنا ،طقس شور و داوم ‌ :اه شوم اه ي CBA/J تفج زا سپ هدام گ ي ر ي شوم اب اه ي رن DBA/2 سقت هورگ ود هب ي م درگ ي ،دند هقب گلماح مجنپ زور رد ومزآ هورگ ي mg/kg 1 س ي روپسولک ي ن ب وراد لماح لرتنک هورگ هب و ه قافص لخاد تروص ي رزت ي ق درگ ي د زور رد 5 / 11 گلماح ي مرس ، مامت ي شوم هت اه ي ه لا شور اب و ي از تنآ ي داب ي اه ي و راقتمان TGF-β1 هزادنا گ ي ر ي مه دش نچ ي ن زور رد طقس دصرد 5 / 11 گلماح ي ب ي ن ا ي ن اب هورگ ود ي ک د ي رگ اقم ي هس درگ ي د هتفاي ‌ :اه م ي از تنآ ي داب ي اه ي ( راقتمان 11 / 1 P< ( طقس دصرد و ) 10 / 1 P< قنعم شهاقک وقمزآ هورگ رد ) ي راد ي ار رد داد اشن لاح ي هک س ي اکوت ي ن TGF-β1 نعم توافت هعلاطم دروم هورگ ود رد ي راد ي ( تشادن 10 / 1 P> ) هجيتن ‌ :يريگ لع ي م شهاک مغر ي از تنآ ي داب ي قنعم تواقفت نتقشادن و وقمزآ هورقگ رد راقتمان ي م رد راد قي از اس ي اکوت ي ن TGF-β1 مرس ي ، م ي از ب لرتنک هورگ هب تبسن ومزآ هورگ رد طقس ه نعم تروص ي شهاک راد ي هتفا تقسا اب اذل ي تس ي ناکم هب ي مس اه ي د ي رگ ا خساپ بوکرس ي نم ي م شهاک و قي از غ طققس قي ر قتنآ زا ي داقب ي اقه ي و راققتمان

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تاریخ انتشار 2016